Ebola Virus Epidemiology and Evolution in Nigeria

نویسندگان

  • Onikepe A. Folarin
  • Deborah Ehichioya
  • Stephen F. Schaffner
  • Sarah M. Winnicki
  • Shirlee Wohl
  • Philomena Eromon
  • Kendra L. West
  • Adrianne Gladden-Young
  • Nicholas E. Oyejide
  • Christian B. Matranga
  • Awa Bineta Deme
  • Ayorinde James
  • Christopher Tomkins-Tinch
  • Kenneth Onyewurunwa
  • Jason T. Ladner
  • Gustavo Palacios
  • Iguosadolo Nosamiefan
  • Kristian G. Andersen
  • Sunday Omilabu
  • Daniel J. Park
  • Nathan L. Yozwiak
  • Abdusallam Nasidi
  • Robert F. Garry
  • Oyewale Tomori
  • Pardis C. Sabeti
  • Christian T. Happi
چکیده

Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Anemia during Hospitalization in the Patients with Ebola Virus Disease

Ebola virus disease is the important emerging disease in Africa. This infection is deadly and has the main clinical feature as an acute hemorrhagic fever. The main hematological alteration in this infection is the platelet change. However, the change in other hematological parameters should be mentioned. 

متن کامل

Contact tracing following outbreak of Ebola virus disease in urban settings in Nigeria

An outbreak of Ebola virus disease occurred in Nigeria between July and September 2014. Contact tracing commenced in Lagos, and extended to Port Harcourt and Enugu as the outbreak continued to spread. A total of 899 contacts were traced. Contact tracing enhanced immediate identification of symptomatic contacts, some of whom eventually became cases. Contact tracing could be challenging in urban ...

متن کامل

COVID-19 Outbreak in Africa: Lessons and Insights from the West African Ebola Virus Disease Epidemics

Over the years, the African continent has had to battle several outbreaks of infectious diseases in different countries. Some of the most deadly were the Ebola virus disease (EVD) outbreaks that occurred in West Africa between 2014 and 2016 affecting Guinea, Liberia, and Sierra Leone and, more recently, from 2018 to 2020 in the Democratic Republic of Congo (DRC). In the era of the COVID-19 pand...

متن کامل

Diarrhea Can Be an Important Clinical Presentation of 2014 Western Africa Ebola Virus Infection

Dear Editor-in-Chief The present global consideration is on the recent outbreak of 2014 Western Ebola virus in West Africa (1 – 3). This viral hemorrhagic fever wide spreads to several countries in West Africa and remote countries (1 - 3). With high death rate, the disease is presently on the list of public health threatens. The main problem for management of the infection is the limited knowl...

متن کامل

Ebola Outbreak in Nigeria: Increasing Ebola Knowledge of Volunteer Health Advisors.

In many low-income countries, volunteer health advisors (VHAs) play an important role in disseminating information, especially in rural or hard-to-reach locations. When the world's largest outbreak of Ebola virus disease (EVD) occurred in 2014, a majority of cases were concentrated in the West African countries of Guinea, Liberia, and Sierra Leone. Twenty cases were reported in Nigeria initiall...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 214  شماره 

صفحات  -

تاریخ انتشار 2016